Plenary Sessions-25/04/2021

Sunday, April 25th, 2021

11:00 - 13:45

Poster Discussion

Poster Session 4 - TREATMENT OF THROMBOSIS

Poster Session 5 - EPIDEMIOLOGY II

Poster Session 6 - THERAPEUTIC CHALLENGES

Poster Session 7 - HEMOSTATIC SYSTEM/TUMOR BIOLOGY INTERACTIONS

15:00 – 16:45

Plenary Session 4: Bench to Bedside: New insights Into Hemostasis and Cancer

Chairs: P.M. Sandset (Norway), R. Giavazzi (Italy)

PL-14 - Genetic and epigenetic regulation of cancer coagulome - lessons from heterogeneity of cancer cell populations
J. Rak (Canada)

PL-15 - Coagulation signaling and cancer immuno-therapy
W. Ruf (Germany)

PL-16 - Heparanase-revisited
Y. Nadir (Israel)

PL-17 - Cancer Animal Models in Thrombosis Research
C. Dubois (France)

PL-18 - The thrombin-inflammation axis in cancer progression
J. Palumbo (USA)

Selected Abstract

OC-10 - Thrombin Tips the Scales towards Effective Immune Checkpoint Blockade in Cancer
R. Cantrell, L. Rosenfeldt, D. Mureb, M. Lehn, B.K. Sharma, A. Revenko, B. Monia, E. Janssen, J.S. Palumbo (USA)

OC-11 - Plasminogen activator inhibitor 1 enhances venous thrombosis in pancreatic cancer
Y. Hisada, K.B. Garratt, A. Maqsood, S.P. Grover, T. Kawano, B.C. Cooley, J. Erlich, F. Moik, M.J. Flick, I. Pabinger, N. Mackman, C. Ay (USA - Austria)

 16:45 – 17:15

Debate: Outpatient prophylaxis: are we there yet?

Chairs: G. Agnelli (Italy), C. Francis (USA)

NO: F. Klok (The Netherlands)

YES: A.A. Khorana (USA)

17:15 – 18:45

Plenary Session 5: Prevention of VTE in cancer patients

Chairs: P. Prandoni (Italy), J.A. Paramo (Spain)

PL-14 - Inpatient thromboprophylaxis in cancer patients: what is the evidence?
J. Zwicker (USA)

PL-15 - Roles of LMWH for prevention in cancer patients
A. Maraveyas (UK)

PL-16 - Meta-analysis and systematic review of NOAC prophylaxis in high risk cancer outpatients
N. Kuderer (USA) 

Selected Abstract

OC-12 - D-dimer levels significantly decline in ambulatory cancer patients receiving rivaroxaban compared to placebo: biomarker analysis of the CASSINI trial
S. Vadhan-Raj, N. Kuderer, T. Wun, J. Patel, K. McCrae, X. Zhou, U. Vijapurkar, C.V. Damaraju, P. Wildgoose, G. Lyman, A.A. Khorana (USA)

OC-13 - A clinical-genetic risk score to predict cancer-associated venous thromboembolism: a development and validation study in two independent prospective cohorts
A. Muñoz, C. Ay, E. Grilz, S. López, C. Font, V. Pachón, V. Castellón, V. Martínez-Marín, M. Salgado, E. Martínez, J. Calzas, A. Rupérez, E. Salas, I. Pabinger, J.M. Soria (Spain, Austria)